In situ fluoride retention and remineralization of incipient carious lesions after the application of different concentrations of fluoride
Publisher DOI
PubMed ID
19196319
Abstract
Limited information is available on the time-dependent or dosage-dependent cariostatic efficacy of highly concentrated fluoride compounds. This good clinical practice-conforming, double-blind, placebo-controlled, crossover in situ study tested the hypothesis that a 1.0% amine fluoride fluid is superior to a 0.5% amine fluoride fluid regarding fluoride retention and mineral change in initial caries enamel lesions over a period of 28 d. Fluoride retention was significantly higher after application of the two fluoride fluids compared with placebo but had decreased in both groups to similar levels after only 1 wk. Mineral gain was significantly higher for both verum groups compared with placebo. The use of 1% fluoride fluid resulted in significantly higher remineralization compared with the use of 0.5% fluoride fluid. For both fluoride fluids mineral gain followed a linear relationship with time during the experimental period, indicating a possible further uptake of mineral, even after 4 wk.
Date Issued
2009
Publication Type
Article
Language(s)
en
Author(s)
Altenburger, Markus J | |
Schirrmeister, Jörg F | |
Klasser, Manfred | |
Hellwig, Elmar |
Additional Credits
Journal
European journal of oral sciences
Publisher
Wiley-Blackwell
ISSN
0909-8836
Access(Rights)
metadata.only