Histopathological alterations of the heart in fish: proposal for a standardized assessment.
Publisher DOI
PubMed ID
27025306
Abstract
Histopathological alterations in the heart are often reported in fish as a result of exposure to a variety of chemical compounds. However, researchers presently lack a standardized method for the evaluation of histopathological alterations in the cardiovascular system of fish and the calculation of an 'organ index'. Therefore, we designed a method for a standardized assessment and evaluation of histopathological alterations in the heart of fish. As a model species, we used rainbow trout Oncorhynchus mykiss, but the protocol was also successfully applied to other fish species belonging to different taxonomic orders. To test the protocol, we re-evaluated sections of atenolol-exposed and unexposed rainbow trout obtained in a previous study. The results were in accordance with those previously published, demonstrating the applicability of the protocol. The protocol provides a universal method for the comparative evaluation of histopathological changes in the heart of fish.
Date Issued
2016-03-30
Publication Type
Article
Subject(s)
Language(s)
en
Author(s)
Additional Credits
Journal
Diseases of aquatic organisms
Publisher
Inter-Research
ISSN
0177-5103
Access(Rights)
open.access