Publication:
Nocardial brain abscess: observation of treatment strategies and outcome in Switzerland from 1992 to 1999

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cris.virtual.author-orcid0000-0002-1106-6123
cris.virtualsource.author-orcidb2be59ff-322b-42b5-8f18-e22b5c2cb3c2
cris.virtualsource.author-orcid1b54a387-db97-41f4-bae6-ad365f708868
datacite.rightsopen.access
dc.contributor.authorLoeffler, Jutta M.
dc.contributor.authorBodmer, Thomas
dc.contributor.authorZimmerli, Werner
dc.contributor.authorLeib, Stephen
dc.date.accessioned2024-10-15T13:58:36Z
dc.date.available2024-10-15T13:58:36Z
dc.date.issued2001-12
dc.description.abstractBACKGROUND Brain abscesses caused by Nocardia spp. are rare, but life-threatening infections that are notoriously difficult to diagnose and treat and which occur mainly in immunocompromised patients. Standard treatment guidelines are not available. METHODS A systematic search for nocardial brain abscesses from 1992 to 1999 was conducted in Switzerland for the comparison of clinical presentation, treatment strategies and outcome. RESULTS Seven cases were found, for which data of six were available. In 4/6 patients antimicrobial therapy led to a decrease in the size of abscesses. Four of six patients died. The cause of death was likely due to underlying co-morbidities, rather than the nocardial infection. CONCLUSION The finding that treatment was different in each case underscores the lack of therapeutic guidelines.
dc.description.numberOfPages5
dc.description.sponsorshipInstitut für Infektionskrankheiten
dc.identifier.doi10.7892/boris.52757
dc.identifier.pmid11787836
dc.identifier.publisherDOI10.1007/s15010-001-1147-1
dc.identifier.urihttps://boris-portal.unibe.ch/handle/20.500.12422/123565
dc.language.isoen
dc.publisherSpringer-Medizin-Verlag
dc.relation.ispartofInfection
dc.relation.issn0300-8126
dc.relation.organizationDCD5A442BD12E17DE0405C82790C4DE2
dc.relation.organizationDCD5A442BDB9E17DE0405C82790C4DE2
dc.subjectNocardia
dc.subjectBrain abscess
dc.subjectAntibiotics
dc.subjectSwitzerland
dc.subject.ddc500 - Science::570 - Life sciences; biology
dc.subject.ddc600 - Technology::610 - Medicine & health
dc.subject.ddc300 - Social sciences, sociology & anthropology::360 - Social problems & social services
dc.titleNocardial brain abscess: observation of treatment strategies and outcome in Switzerland from 1992 to 1999
dc.typearticle
dspace.entity.typePublication
dspace.file.typetext
oaire.citation.endPage341
oaire.citation.issue6
oaire.citation.startPage337
oaire.citation.volume29
oairecerif.author.affiliationInstitut für Infektionskrankheiten
oairecerif.author.affiliationInstitut für Infektionskrankheiten
unibe.contributor.rolecreator
unibe.contributor.rolecreator
unibe.contributor.rolecreator
unibe.contributor.rolecreator
unibe.description.ispublishedpub
unibe.eprints.legacyId52757
unibe.journal.abbrevTitleINFECTION
unibe.refereedtrue
unibe.subtype.articlejournal

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