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  3. Positioning biologics in the treatment of IBD: A practical guide - Which mechanism of action for whom?

Positioning biologics in the treatment of IBD: A practical guide - Which mechanism of action for whom?

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DOI
10.48350/170079
Publisher DOI
10.1016/j.crphar.2022.100104
PubMed ID
35570855
Abstract
The number of available biological therapies have doubled over the last 10 years and the arrival of novel molecules (interleukin 23p19 inhibitors) is ongoing alongside the development of small molecules. As a result of this vast landscape of treatment, positioning advanced therapies (according to clinical situation, efficacy and safety) is of paramount importance to providing personalized, appropriate IBD treatment. In this publication the recent available literature is summarized for practical integration into clinical practice including comparative efficacy data, patient and disease demographics. We refer to recent publications and expert opinion in order to facilitate the decision making process of positioning biologicals IBD treatment.
Date Issued
2022-05-05
Publication Type
Article
Subject(s)
600 Technology > 610 Medicine & health
Subjects
Adalimumab Biological therapy Infliximab Monoclonal antibodies Ustekinumab Vedolizumab
Language(s)
en
Author(s)
Juillerat, Pascal  
Universitätsklinik für Viszerale Chirurgie und Medizin, Gastroenterologie  
Martinho-Grüber, Maude Delphine  
Universitätsklinik für Viszerale Chirurgie und Medizin  
Ruetsch, Roseline
Santi, Giulia  
Universitätsklinik für Viszerale Chirurgie und Medizin  
Vuillèmoz, Marianne
Michetti, Pierre
Additional Credits
Universitätsklinik für Viszerale Chirurgie und Medizin, Gastroenterologie  
Universitätsklinik für Viszerale Chirurgie und Medizin  
Journal
Current research in pharmacology and drug discovery
Publisher
Elsevier
ISSN
2590-2571
Access(Rights)
Unknown
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