Additive effect of homocysteine- and cholesterol-lowering therapy on endothelium-dependent vasodilation in patients with cardiovascular disease
Publisher DOI
PubMed ID
21884007
Abstract
Endothelial dysfunction is a marker for development and progression of atherosclerosis. Statin therapy improves endothelial function in cardiovascular patients by reducing LDL-cholesterol and by pleiotropic effects. B-group vitamin supplementation restores endothelial function mainly by reducing homocysteine-induced oxidative stress. Thus, we evaluated the effect of rosuvastatin, B-group vitamins and their combination on endothelial function in high-risk cardiovascular patients.
Date Issued
2012
Publication Type
Article
Language(s)
en
Author(s)
Additional Credits
Journal
Cardiovascular therapeutics
Publisher
Blackwell
ISSN
1755-5914
Access(Rights)
metadata.only