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  3. Outcome of elderly patients undergoing primary percutaneous coronary intervention for acute ST-elevation myocardial infarction

Outcome of elderly patients undergoing primary percutaneous coronary intervention for acute ST-elevation myocardial infarction

Details
Publisher DOI
10.1002/ccd.21128
PubMed ID
17894363
Abstract
AIM: To investigate the outcome of primary percutaneous coronary interventions (PCI) in elderly patients (>/=>/=75 years) with ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS: Between 1995 and 2003, a total of 319 consecutive patients with acute ST-elevation myocardial infarction presenting within 6-12 hr after onset of symptoms were prospectively enrolled in a registry. Of 296 patients undergoing primary PCI, 40 patients were >/=>/=75 years old (group A) and 256 patients younger than 75 years (group B). Elderly patients presented with a lower ejection fraction (49 +/- 14% vs. 53 +/- 13%, P = 0.046) and a higher number of cardiovascular risk factors. PCI success was achieved in 80% (group A) and 91% (group B, P = 0.031), respectively with comparable door-to-balloon times (87 +/- 49 and 95 +/- 79 min, P = ns). Periprocedural complications in both groups were low and major adverse cardiac events (death, myocardial infarction, target vessel revascularization and cardiac rehospitalization) after 6 months amounted to 23% (group A) and 20% (group B, P = ns), respectively. CONCLUSIONS: Clinical outcome of elderly patients (>/=>/=75 years) with acute STEMI is favorable and comparable with the middle-aged population. However, procedural success was significantly lower in elderly (80%) compared to younger patients (90%). Acute percutaneous coronary intervention appears to be safe and not associated with higher periprocedural complications, in elderly patients.
Date Issued
2007
Publication Type
Article
Language(s)
en
Author(s)
Wenaweser, Peter Martin  
Universitätsklinik für Kardiologie  
Ramser, Marianne
Windecker, Stephan  
Universitätsklinik für Kardiologie  
Lütolf, Indira
Meier, Bernhard  
Universitätsklinik für Kardiologie  
Seiler, Christian  
Universitätsklinik für Kardiologie  
Eberli, Franz  
Universitätsklinik für Kardiologie  
Hess, Otto  
Universitätsklinik für Kardiologie  
Additional Credits
Universitätsklinik für Kardiologie  
Journal
Catheterization and cardiovascular interventions
Publisher
Wiley-Blackwell
ISSN
1522-1946
ISBN
17894363
Access(Rights)
metadata.only
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